PIN1 Provides Dynamic Control of MYC in Response to Extrinsic Signals

PIN1 is a phosphorylation-directed member of the peptidyl-prolyl cis/trans isomerase (PPIase) family that facilitates conformational changes in phosphorylated targets such as c-MYC (MYC). Following signaling events that mediate phosphorylation of MYC at Serine 62, PIN1 establishes structurally disti...

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Main Authors: Gabriel M. Cohn, Daniel F. Liefwalker, Ellen M. Langer, Rosalie C. Sears
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-04-01
Colecção:Frontiers in Cell and Developmental Biology
Assuntos:
Pin1
c-Myc
nuclear pore complex
phosphorylation
isomerization
Acesso em linha:https://www.frontiersin.org/article/10.3389/fcell.2020.00224/full
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