Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression

High expression of the oncoprotein Myc has been linked to poor outcome in human tumors. Although MYC gene amplification and translocations have been observed, this can explain Myc overexpression in only a subset of human tumors. Myc expression is in part controlled by its protein stability, which ca...

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Detalhes bibliográficos
Main Authors: Zhang, Xiaoli, Farrell, Amy S., Daniel, Colin J., Arnold, Hugh, Scanlan, Charles, Laraway, Bryan J., Janghorban, Mahnaz, Lum, Lawrence, Chen, Dexi, Troxell, Megan, Sears, Rosalie
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Breast Cancer Special Feature
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286933/
https://ncbi.nlm.nih.gov/pubmed/21808024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100764108
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