The Axin1 scaffold protein promotes formation of a degradation complex for c-Myc

Expression of the c-Myc proto-oncoprotein is tightly regulated in normal cells. Phosphorylation at two conserved residues, threonine58 (T58) and serine62 (S62), regulates c-Myc protein stability. In cancer cells, c-Myc can become aberrantly stabilized associated with altered T58 and S62 phosphorylat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Arnold, Hugh K, Zhang, Xiaoli, Daniel, Colin J, Tibbitts, Deanne, Escamilla-Powers, Julie, Farrell, Amy, Tokarz, Sara, Morgan, Charlie, Sears, Rosalie C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657573/
https://ncbi.nlm.nih.gov/pubmed/19131971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.279
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak