Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression

High expression of the oncoprotein Myc has been linked to poor outcome in human tumors. Although MYC gene amplification and translocations have been observed, this can explain Myc overexpression in only a subset of human tumors. Myc expression is in part controlled by its protein stability, which ca...

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Main Authors: Zhang, Xiaoli, Farrell, Amy S., Daniel, Colin J., Arnold, Hugh, Scanlan, Charles, Laraway, Bryan J., Janghorban, Mahnaz, Lum, Lawrence, Chen, Dexi, Troxell, Megan, Sears, Rosalie
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2012
נושאים:
Breast Cancer Special Feature
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286933/
https://ncbi.nlm.nih.gov/pubmed/21808024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100764108
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