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Complications from Dual Roles of Sodium Hydride as a Base and as a Reducing Agent
[Image: see text] Sodium hydride is a common reagent for substrate activation in nucleophilic substitution reactions. Sodium hydride can behave both as a base and as a source of hydride. This dual ability in the presence of an electrophile such as benzyl bromide results in the formation of byproduct...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3286627/ https://ncbi.nlm.nih.gov/pubmed/19215116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo802706d |
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