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Single-molecule mRNA decay measurements reveal promoter regulated mRNA stability in yeast

Messenger RNA decay measurements are typically performed on a population of cells. However, this approach cannot reveal sufficient complexity to provide information on mechanisms that may regulate mRNA degradation, possibly on short time scales. To address this deficiency, we measured cell cycle reg...

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Autors principals: Trcek, Tatjana, Larson, Daniel R., Moldón, Alberto, Query, Charles C., Singer, Robert H.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286490/
https://ncbi.nlm.nih.gov/pubmed/22196726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.11.051
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