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The disulfide isomerase ERp57 mediates platelet aggregation, hemostasis, and thrombosis
A close homologue to protein disulfide isomerase (PDI) called ERp57 forms disulfide bonds in glycoproteins in the endoplasmic reticulum and is expressed on the platelet surface. We generated 2 rabbit Abs to ERp57. One Ab strongly inhibited ERp57 in a functional assay and strongly inhibited platelet...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3286349/ https://ncbi.nlm.nih.gov/pubmed/22207737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-360685 |
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