Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia

The chemokine receptor CXCR4, which normally regulates stromal stem cell interactions in the bone marrow, is highly expressed on a variety of malignant hematologic cells, including lymphoma and lymphocytic leukemias. A new treatment concept has arisen wherein CXCR4 may be an effective therapeutic ta...

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Bibliographic Details
Main Authors: O'Callaghan, Katie, Lee, Lydia, Nguyen, Nga, Hsieh, Mo-Ying, Kaneider, Nicole C., Klein, Andreas K., Sprague, Kellie, Van Etten, Richard A., Kuliopulos, Athan, Covic, Lidija
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2012
Subjects:
Lymphoid Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286348/
https://ncbi.nlm.nih.gov/pubmed/22186993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-347518
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