uPAR and Cathepsin B Downregulation Induces Apoptosis by Targeting Calcineurin A to BAD via Bcl-2 in Glioma

Cathepsin B and urokinase plasminogen activator receptor (uPAR) are postulated to play key roles in glioma invasion. Calcineurin is one of the key regulators of mitochondrial-dependent apoptosis, but its mechanism is poorly understood. Hence, we studied subcellular localization of calcineurin after...

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Библиографические подробности
Главные авторы: Malla, Rama Rao, Gopinath, Sreelatha, Gondi, Christopher S., Alapati, Kiranmai, Dinh, Dzung H., Tsung, Andrew J., Rao, Jasti S.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286222/
https://ncbi.nlm.nih.gov/pubmed/21964739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-011-0727-x
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