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Binding of filamentous actin to anthrax toxin receptor 1 decreases its association with protective antigen

ANTXR1 is a Type I membrane protein that binds the protective antigen (PA) component of anthrax toxin. The cytosolic domain of ANTXR1 has a novel actin-binding region that influences the interaction of the ectodomain with PA. Here, we have investigated features of the cytosolic domain of ANTXR1 that...

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Bibliographische Detailangaben
Hauptverfasser: Garlick, Kristopher M., Batty, Sarah, Mogridge, Jeremy
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3286128/
https://ncbi.nlm.nih.gov/pubmed/22303962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2016469
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