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Direct Interaction between Anthrax Toxin Receptor 1 and the Actin Cytoskeleton

The protective antigen component of anthrax toxin binds the I domain of the anthrax toxin receptors, ANTXR1 and ANTXR2, in a manner akin to how integrins bind their ligands. The I domains of integrins and ANTXR1 both have high and low affinity conformations and the cytosolic tails of these receptors...

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Detalhes bibliográficos
Main Authors: Garlick, Kristopher M., Mogridge, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847348/
https://ncbi.nlm.nih.gov/pubmed/19817382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9015296
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