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The Cytoplasmic Domain of Anthrax Toxin Receptor 1 Affects Binding of the Protective Antigen

The protective antigen (PA) component of anthrax toxin binds the I domain of the receptor ANTXR1. Integrin I domains convert between open and closed conformations that bind ligand with high and low affinities, respectively; this process is regulated by signaling from the cytoplasmic domains. To asse...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Go, Mandy Y., Chow, Edith M. C., Mogridge, Jeremy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612287/
https://ncbi.nlm.nih.gov/pubmed/18936178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01073-08
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