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Involvement of Domain 3 in Oligomerization by the Protective Antigen Moiety of Anthrax Toxin
Protective antigen (PA), a component of anthrax toxin, binds receptors on mammalian cells and is activated by a cell surface protease. The resulting active fragment, PA(63), forms ring-shaped heptamers, binds the enzymic moieties of the toxin, and translocates them to the cytosol. Of the four crysta...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC95109/ https://ncbi.nlm.nih.gov/pubmed/11222612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.6.2111-2116.2001 |
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