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Mapping the lethal factor and edema factor binding sites on oligomeric anthrax protective antigen

Assembly of anthrax toxin complexes at the mammalian cell surface involves competitive binding of the edema factor (EF) and lethal factor (LF) to heptameric oligomers and lower order intermediates of PA(63), the activated carboxyl-terminal 63-kDa fragment of protective antigen (PA). We used sequence...

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Detalhes bibliográficos
Main Authors: Cunningham, Kristina, Lacy, D. Borden, Mogridge, Jeremy, Collier, R. John
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC124526/
https://ncbi.nlm.nih.gov/pubmed/11997439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.062160399
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