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The Cytoplasmic Domain of Anthrax Toxin Receptor 1 Affects Binding of the Protective Antigen
The protective antigen (PA) component of anthrax toxin binds the I domain of the receptor ANTXR1. Integrin I domains convert between open and closed conformations that bind ligand with high and low affinities, respectively; this process is regulated by signaling from the cytoplasmic domains. To asse...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2612287/ https://ncbi.nlm.nih.gov/pubmed/18936178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01073-08 |
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