The impact of cyclin-dependent kinase 5 depletion on poly(ADP-ribose) polymerase activity and responses to radiation

Cyclin-dependent kinase 5 (Cdk5) has been identified as a determinant of sensitivity to poly(ADP-ribose) polymerase (PARP) inhibitors. Here, the consequences of its depletion on cell survival, PARP activity, the recruitment of base excision repair (BER) proteins to DNA damage sites, and overall DNA...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Bolin, Celeste, Boudra, Mohammed-Tayyib, Fernet, Marie, Vaslin, Laurence, Pennaneach, Vincent, Zaremba, Tomasz, Biard, Denis, Cordelières, Fabrice P., Favaudon, Vincent, Mégnin-Chanet, Frédérique, Hall, Janet
Format: Artigo
Jezik:Inglês
Izdano: SP Birkhäuser Verlag Basel 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285760/
https://ncbi.nlm.nih.gov/pubmed/21922195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-011-0811-6
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki