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Regulation of Toll-like receptor signaling by NDP52-mediated selective autophagy is normally inactivated by A20
Toll-like receptor (TLR) signaling is linked to autophagy that facilitates elimination of intracellular pathogens. However, it is largely unknown whether autophagy controls TLR signaling. Here, we report that poly(I:C) stimulation induces selective autophagic degradation of the TLR adaptor molecule...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
SP Birkhäuser Verlag Basel
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285758/ https://ncbi.nlm.nih.gov/pubmed/21964925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-011-0819-y |
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