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Apurinic/Apyrimidinic Endonuclease Is Inversely Associated with Response to Radiotherapy in Pediatric Ependymoma

Apurinic/apyrimidinic endonuclease (Ap endo) is a key DNA repair activity that confers radiation resistance in human cells. Here we examined the association between Ap endo activity and response to radiotherapy in pediatric ependymomas, tumors for which treatment options are limited and survival rat...

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Detalhes bibliográficos
Main Authors: Bobola, Michael S., Jankowski, Pawel, Gross, Mary E., Schwartz, Jeffery, Finn, Laura S., Blank, A., Ellenbogen, Richard G., Silber, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285472/
https://ncbi.nlm.nih.gov/pubmed/21207372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25900
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