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Glypican-1 Stimulates Skp2 Autoinduction Loop and G(1)/S Transition in Endothelial Cells

The heparan sulfate proteoglycan glypican-1 (GPC1) is involved in tumorigenesis and angiogenesis and is overexpressed frequently in tumor and endothelial cells (ECs) in human gliomas. We demonstrated previously that in brain EC, GPC1 regulates mitotic cyclins and securin as well as mitosis and that...

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Hlavní autoři: Qiao, Dianhua, Meyer, Kristy, Friedl, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285358/
https://ncbi.nlm.nih.gov/pubmed/22203671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.325282
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