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Glypican 1 Stimulates S Phase Entry and DNA Replication in Human Glioma Cells and Normal Astrocytes

Malignant gliomas are highly lethal neoplasms with limited treatment options. We previously found that the heparan sulfate proteoglycan glypican 1 (GPC1) is universally and highly expressed in human gliomas. In this study, we investigated the biological activity of GPC1 expression in both human glio...

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Bibliographic Details
Main Authors: Qiao, Dianhua, Meyer, Kristy, Friedl, Andreas
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838173/
https://ncbi.nlm.nih.gov/pubmed/24019070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00238-13
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