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Glypican-1 Stimulates Skp2 Autoinduction Loop and G(1)/S Transition in Endothelial Cells
The heparan sulfate proteoglycan glypican-1 (GPC1) is involved in tumorigenesis and angiogenesis and is overexpressed frequently in tumor and endothelial cells (ECs) in human gliomas. We demonstrated previously that in brain EC, GPC1 regulates mitotic cyclins and securin as well as mitosis and that...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285358/ https://ncbi.nlm.nih.gov/pubmed/22203671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.325282 |
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