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The RAF Inhibitor Paradox Revisited

The success of the RAF protein kinase inhibitor vemurafenib for the treatment of BRAF-mutant metastatic melanoma has produced another poster child for the promise of personalized medicine. However, the results of a recent study also reveal unexpected pitfalls in the application of signal transductio...

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Bibliografiske detaljer
Main Authors: Cox, Adrienne D., Der, Channing J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285264/
https://ncbi.nlm.nih.gov/pubmed/22340588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.01.017
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