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The RAF Inhibitor Paradox Revisited
The success of the RAF protein kinase inhibitor vemurafenib for the treatment of BRAF-mutant metastatic melanoma has produced another poster child for the promise of personalized medicine. However, the results of a recent study also reveal unexpected pitfalls in the application of signal transductio...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3285264/ https://ncbi.nlm.nih.gov/pubmed/22340588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.01.017 |
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