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Human papillomavirus 18 E6 inhibits phosphorylation of p53 expressed in HeLa cells

BACKGROUND: In HPV infected cells p53 function is abrogated by E6 and even ectopically expressed p53 is unable to perform tumor suppressor functions. In addition to facilitating its degradation, E6 may also inhibit p53 transactivity, though the mechanisms are still poorly understood. It has been rep...

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Détails bibliographiques
Auteurs principaux: Ajay, Amrendra K, Meena, Avtar S, Bhat, Manoj K
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3285035/
https://ncbi.nlm.nih.gov/pubmed/22244155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-2-2
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