Cdk5 phosphorylates non-genotoxically overexpressed p53 following inhibition of PP2A to induce cell cycle arrest/apoptosis and inhibits tumor progression

BACKGROUND: p53 is the most studied tumor suppressor and its overexpression may or may not cause cell death depending upon the genetic background of the cells. p53 is degraded by human papillomavirus (HPV) E6 protein in cervical carcinoma. Several stress activated kinases are known to phosphorylate...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Ajay, Amrendra K, Upadhyay, Ankur K, Singh, Sandeep, Vijayakumar, Maleppillil V, Kumari, Ratna, Pandey, Vimal, Boppana, Ramanamurthy, Bhat, Manoj K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922192/
https://ncbi.nlm.nih.gov/pubmed/20673369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-204
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados