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Volume Exclusion and H-Bonding Dominate the Thermodynamics and Solvation of Trimethylamine-N-oxide in Aqueous Urea
[Image: see text] Trimethylamine-N-oxide (TMAO) and urea represent the extremes among the naturally occurring organic osmolytes in terms of their ability to stabilize/destabilize proteins. Their mixtures are found in nature and have generated interest in terms of both their physiological role and th...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2012
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3284192/ https://ncbi.nlm.nih.gov/pubmed/22280147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja211530n |
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