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Counteraction of Urea by Trimethylamine N-Oxide Is Due to Direct Interaction
Trimethylamine N-oxide (TMAO) is a naturally occurring osmolyte that stabilizes proteins, induces folding, and counteracts the denaturing effects of urea, pressure, and ice. To establish the mechanism behind these effects, isotopic substitution neutron-scattering measurements were performed on aqueo...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Biophysical Society
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770612/ https://ncbi.nlm.nih.gov/pubmed/19883599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.08.017 |
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