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Counteraction of Urea by Trimethylamine N-Oxide Is Due to Direct Interaction
Trimethylamine N-oxide (TMAO) is a naturally occurring osmolyte that stabilizes proteins, induces folding, and counteracts the denaturing effects of urea, pressure, and ice. To establish the mechanism behind these effects, isotopic substitution neutron-scattering measurements were performed on aqueo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2770612/ https://ncbi.nlm.nih.gov/pubmed/19883599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.08.017 |
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