Effects of trimethylamine N-oxide and urea on DNA duplex and G-quadruplex

We systematically investigated effects of molecular crowding with trimethylamine N-oxide (TMAO) as a zwitterionic and protective osmolyte and urea as a nonionic denaturing osmolyte on conformation and thermodynamics of the canonical DNA duplex and the non-canonical DNA G-quadruplex. It was found tha...

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Bibliografische gegevens
Gepubliceerd in:Sci Technol Adv Mater
Hoofdauteurs: Ueda, Yu-mi, Zouzumi, Yu-ki, Maruyama, Atsushi, Nakano, Shu-ichi, Sugimoto, Naoki, Miyoshi, Daisuke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2016
Onderwerpen:
Focus on Nanomedicine molecular science
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127293/
https://ncbi.nlm.nih.gov/pubmed/27933115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14686996.2016.1243000
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