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A mRNA-Responsive G-Quadruplex-Based Drug Release System
G-quadruplex-based drug delivery carriers (GDDCs) were designed to capture and release a telomerase inhibitor in response to a target mRNA. Hybridization between a loop on the GDDC structure and the mRNA should cause the G-quadruplex structure of the GDDC to unfold and release the bound inhibitor, a...
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| Udgivet i: | Sensors (Basel) |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4431183/ https://ncbi.nlm.nih.gov/pubmed/25905703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/s150409388 |
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