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Volume Exclusion and H-Bonding Dominate the Thermodynamics and Solvation of Trimethylamine-N-oxide in Aqueous Urea

[Image: see text] Trimethylamine-N-oxide (TMAO) and urea represent the extremes among the naturally occurring organic osmolytes in terms of their ability to stabilize/destabilize proteins. Their mixtures are found in nature and have generated interest in terms of both their physiological role and th...

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Detalhes bibliográficos
Main Authors: Rösgen, Jörg, Jackson-Atogi, Ruby
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3284192/
https://ncbi.nlm.nih.gov/pubmed/22280147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja211530n
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