Low-Resolution Molecular Models Reveal the Oligomeric State of the PPAR and the Conformational Organization of Its Domains in Solution

The peroxisome proliferator-activated receptors (PPARs) regulate genes involved in lipid and carbohydrate metabolism, and are targets of drugs approved for human use. Whereas the crystallographic structure of the complex of full length PPARγ and RXRα is known, structural alterations induced by heter...

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Detaylı Bibliyografya
Asıl Yazarlar: Bernardes, Amanda, Batista, Fernanda A. H., de Oliveira Neto, Mario, Figueira, Ana Carolina M., Webb, Paul, Saidemberg, Daniel, Palma, Mario S., Polikarpov, Igor
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283691/
https://ncbi.nlm.nih.gov/pubmed/22363753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031852
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