Structural Insights into Human Peroxisome Proliferator Activated Receptor Delta (PPAR-Delta) Selective Ligand Binding

Peroxisome proliferator activated receptors (PPARs δ, α and γ) are closely related transcription factors that exert distinct effects on fatty acid and glucose metabolism, cardiac disease, inflammatory response and other processes. Several groups developed PPAR subtype specific modulators to trigger...

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Bibliographic Details
Main Authors: Batista, Fernanda A. H., Trivella, Daniela B. B., Bernardes, Amanda, Gratieri, Joyce, Oliveira, Paulo S. L., Figueira, Ana Carolina M., Webb, Paul, Polikarpov, Igor
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3350516/
https://ncbi.nlm.nih.gov/pubmed/22606221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033643
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