Cellular and Biophysical Pipeline for the Screening of Peroxisome Proliferator-Activated Receptor Beta/Delta Agonists: Avoiding False Positives

Peroxisome proliferator-activated receptor beta/delta (PPARß/δ) is considered a therapeutic target for metabolic disorders, cancer, and cardiovascular diseases. Here, we developed one pipeline for the screening of PPARß/δ agonists, which reduces the cost, time, and false-positive hits. The first ste...

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Bibliographische Detailangaben
Veröffentlicht in:PPAR Res
Hauptverfasser: Videira, Natália Bernardi, Batista, Fernanda Aparecida Heleno, Torres Cordeiro, Artur, Figueira, Ana Carolina Migliorini
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924986/
https://ncbi.nlm.nih.gov/pubmed/29849537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3681590
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