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Transcriptional Repressor NIR Functions in the Ribosome RNA Processing of Both 40S and 60S Subunits
BACKGROUND: NIR was identified as an inhibitor of histone acetyltransferase and it represses transcriptional activation of p53. NIR is predominantly localized in the nucleolus and known as Noc2p, which is involved in the maturation of the 60S ribosomal subunit. However, how NIR functions in the nucl...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3282729/ https://ncbi.nlm.nih.gov/pubmed/22363708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031692 |
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