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1A6/DRIM, a Novel t-UTP, Activates RNA Polymerase I Transcription and Promotes Cell Proliferation

BACKGROUND: Ribosome biogenesis is required for protein synthesis and cell proliferation. Ribosome subunits are assembled in the nucleolus following transcription of a 47S ribosome RNA precursor by RNA polymerase I and rRNA processing to produce mature 18S, 28S and 5.8S rRNAs. The 18S rRNA is incorp...

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Detalhes bibliográficos
Main Authors: Peng, Qunhui, Wu, Jianguo, Zhang, Ying, Liu, Yun, Kong, Ruirui, Hu, Lelin, Du, Xiaojuan, Ke, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998426/
https://ncbi.nlm.nih.gov/pubmed/21151873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014244
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