Chargement en cours...

A Small Ribosomal Subunit (SSU) Processome Component, the Human U3 Protein 14A (hUTP14A) Binds p53 and Promotes p53 Degradation

Ribosome biogenesis is required for normal cell function, and aberrant ribosome biogenesis can lead to p53 activation. However, how p53 is activated by defects of ribosome biogenesis remains to be determined. Here, we identified human UTP14a as an SSU processome component by showing that hUTP14a is...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Hu, Lelin, Wang, Jiangnan, Liu, Yun, Zhang, Ying, Zhang, Liangliang, Kong, Ruirui, Zheng, Zongfang, Du, Xiaojuan, Ke, Yang
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024804/
https://ncbi.nlm.nih.gov/pubmed/21078665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.157842
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!