Cargando...

A Small Ribosomal Subunit (SSU) Processome Component, the Human U3 Protein 14A (hUTP14A) Binds p53 and Promotes p53 Degradation

Ribosome biogenesis is required for normal cell function, and aberrant ribosome biogenesis can lead to p53 activation. However, how p53 is activated by defects of ribosome biogenesis remains to be determined. Here, we identified human UTP14a as an SSU processome component by showing that hUTP14a is...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Hu, Lelin, Wang, Jiangnan, Liu, Yun, Zhang, Ying, Zhang, Liangliang, Kong, Ruirui, Zheng, Zongfang, Du, Xiaojuan, Ke, Yang
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024804/
https://ncbi.nlm.nih.gov/pubmed/21078665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.157842
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!