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Breakdown in Peripheral Tolerance in Type 1 Diabetes in Mice and Humans

Type 1 Diabetes (T1D), also called juvenile diabetes because of its classically early onset, is considered an autoimmune disease targeting the insulin-producing β cells in the pancreatic islets of Langerhans. T1D reflects a loss of tolerance to tissue self-antigens caused by defects in both central...

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מידע ביבליוגרפי
Main Authors: Jeker, Lukas T., Bour-Jordan, Hélène, Bluestone, Jeffrey A.
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282496/
https://ncbi.nlm.nih.gov/pubmed/22393537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a007807
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