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Breakdown in Peripheral Tolerance in Type 1 Diabetes in Mice and Humans
Type 1 Diabetes (T1D), also called juvenile diabetes because of its classically early onset, is considered an autoimmune disease targeting the insulin-producing β cells in the pancreatic islets of Langerhans. T1D reflects a loss of tolerance to tissue self-antigens caused by defects in both central...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2012
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3282496/ https://ncbi.nlm.nih.gov/pubmed/22393537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a007807 |
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