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B cell depletion: a novel therapy for autoimmune diabetes?

Autoimmune diabetes is believed to be mediated primarily by T cells. However, B cells have been implicated in the pathogenesis of the disease in NOD mice. Although preclinical studies have been limited by the absence of anti-CD20 reagents that can induce B cell depletion in mice, a clinical trial us...

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Detaylı Bibliyografya
Asıl Yazarlar: Bour-Jordan, Hélène, Bluestone, Jeffrey A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2096437/
https://ncbi.nlm.nih.gov/pubmed/18060022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34236
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