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Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells

Costimulation is a concept that goes back to the early 1980’s when Lafferty and others hypothesized that cell surface and soluble molecules must exist that are essential for initiating immune responses subsequent to antigen exposure. The explosion in this field of research ensued as over a dozen mol...

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Detalhes bibliográficos
Main Authors: Bour-Jordan, Hélène, Bluestone, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714548/
https://ncbi.nlm.nih.gov/pubmed/19426214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2009.00775.x
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