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Impact of the TCR Signal on Regulatory T Cell Homeostasis, Function, and Trafficking

Signaling through the T cell antigen receptor (TCR) is important for the homeostasis of naïve and memory CD4(+) T cells. The significance of TCR signaling in regulatory T (Treg) cells has not been systematically addressed. Using an Ox40-cre allele that is prominently expressed in Treg cells, and a c...

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Autori principali: Kim, Joong Kyu, Klinger, Mark, Benjamin, Jonathan, Xiao, Yuanyuan, Erle, David J., Littman, Dan R., Killeen, Nigel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719063/
https://ncbi.nlm.nih.gov/pubmed/19668367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006580
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