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B cell depletion: a novel therapy for autoimmune diabetes?
Autoimmune diabetes is believed to be mediated primarily by T cells. However, B cells have been implicated in the pathogenesis of the disease in NOD mice. Although preclinical studies have been limited by the absence of anti-CD20 reagents that can induce B cell depletion in mice, a clinical trial us...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2096437/ https://ncbi.nlm.nih.gov/pubmed/18060022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34236 |
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