Sequence requirements for mammalian topoisomerase II mediated DNA cleavage stimulated by an ellipticine derivative.

Various antitumor drugs stabilize DNA topoisomerase II-DNA transient covalent complexes. The complexes distribution along pBR322 DNA was shown previously to depend upon the nature of the drug (Tewey et al. (1984) Science 226, 466-468). The position in pBR322 of DNA cleavage by calf DNA topoisomerase...

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Detalles Bibliográficos

Publicado en:	Nucleic Acids Res
Principais autores:	Fossé, P, René, B, Le Bret, M, Paoletti, C, Saucier, J M
Formato:	Artigo
Idioma:	Inglês
Publicado:	Oxford University Press 1991
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328243/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1647520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.11.2861
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