Base sequence determinants of amonafide stimulation of topoisomerase II DNA cleavage.
A number of antitumor drugs including naphthalimides, a new class of intercalating agents, interfere with the DNA breakage-reunion activity of mammalian DNA topoisomerase II resulting in DNA cleavage stimulation. In this work, the sequence specificity of a lead compound of this series, amonafide, in...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306658/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862525/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.2.223 |
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