Sequence requirements for mammalian topoisomerase II mediated DNA cleavage stimulated by an ellipticine derivative.
Various antitumor drugs stabilize DNA topoisomerase II-DNA transient covalent complexes. The complexes distribution along pBR322 DNA was shown previously to depend upon the nature of the drug (Tewey et al. (1984) Science 226, 466-468). The position in pBR322 of DNA cleavage by calf DNA topoisomerase...
Guardat en:
| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1991
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| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC328243/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1647520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.11.2861 |
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