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A Novel Class of Small Molecule Inhibitors of Hsp90
Unregulated cellular proliferation, caused by mutation or dysregulation of growth-promoting proteins, is an underlying cause of cancer. Many such growth-promoting proteins exhibit an increased dependence on the activity of the chaperone heat-shock protein 90 (Hsp90) for correct folding and maturatio...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3282108/ https://ncbi.nlm.nih.gov/pubmed/18785742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb800162x |
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