Metformin: Multi-faceted protection against cancer

The biguanide metformin, a widely used drug for the treatment of type 2 diabetes, may exert cancer chemopreventive effects by suppressing the transformative and hyperproliferative processes that initiate carcinogenesis. Metformin's molecular targets in cancer cells (e.g., mTOR, HER2) are simila...

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Main Authors: Del Barco, Sonia, Vazquez-Martin, Alejandro, Cufí, Sílvia, Oliveras-Ferraros, Cristina, Bosch-Barrera, Joaquim, Joven, Jorge, Martin-Castillo, Begoña, Menendez, Javier A.
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282095/
https://ncbi.nlm.nih.gov/pubmed/22203527
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