DRB1*03:01 Haplotypes: Differential Contribution to Multiple Sclerosis Risk and Specific Association with the Presence of Intrathecal IgM Bands

BACKGROUND: Multiple sclerosis (MS) is a multifactorial disease with a genetic basis. The strongest associations with the disease lie in the Human Leukocyte Antigen (HLA) region. However, except for the DRB1*15:01 allele, the main risk factor associated to MS so far, no consistent effect has been de...

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Main Authors: de la Concha, Emilio G., Cavanillas, María L., Cénit, M. Carmen, Urcelay, Elena, Arroyo, Rafael, Fernández, Óscar, Álvarez-Cermeño, José C., Leyva, Laura, Villar, Luisa M., Núñez, Concepción
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281895/
https://ncbi.nlm.nih.gov/pubmed/22363536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031018
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