N-Methyl-d-aspartate Receptor Mechanosensitivity Is Governed by C Terminus of NR2B Subunit

N-Methyl-d-aspartate receptors (NMDARs), critical mediators of both physiologic and pathologic neurological signaling, have previously been shown to be sensitive to mechanical stretch through the loss of its native Mg(2+) block. However, the regulation of this mechanosensitivity has yet to be furthe...

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Autores principales: Singh, Pallab, Doshi, Shachee, Spaethling, Jennifer M., Hockenberry, Adam J., Patel, Tapan P., Geddes-Klein, Donna M., Lynch, David R., Meaney, David F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Neurobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281702/
https://ncbi.nlm.nih.gov/pubmed/22179603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253740
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